PoE2 Unveils "Slithering Dead" Quest Guide

This guide covers the "Slithering Dead" side quest in Path of Exile 2, focusing on its walkthrough and reward choices.

Quick Links

• The Slithering Dead Quest Walkthrough (Step-by-Step)
• Choosing Your Venom Draught Reward in The Slithering Dead

The Slithering Dead, initiated by Servi in the Ziggurat Encampment, tasks players with uncovering the fate of her son and the secrets of a rival tribe. While the quest's progression is straightforward, selecting the right reward presents a challenge. The choice is permanent and irreversible.

The Slithering Dead Quest Walkthrough (Step-by-Step)

To begin, locate the Venom Crypts entrance within the Act 3 (and Act 3 Cruel) Jungle Ruins map, adjacent to the Waypoint. The Venom Crypts are an optional area, not crucial for main storyline progression. You can revisit it even after completing the main story.

Explore the Venom Crypts until you find a corpse in the Den of the Serpent Priestess (location varies due to map randomization).

Interact with the corpse to obtain Corpse-Snake Venom. Return to Servi in the Ziggurat Encampment and deliver the venom to complete the quest.

Choosing Your Venom Draught Reward in The Slithering Dead

The Slithering Dead is repeatable, appearing in both Act 3 and Act 3 Cruel (Act 6). Rewards differ between acts, making each choice unique.

Act 3 Reward Choices

Servi offers three Venom Draughts:

The Venom Draught of Clarity is generally the best choice, particularly beneficial for mana-intensive melee builds. The Venom Draught of the Veil is a strong alternative for builds less reliant on mana. The Venom Draught of Stone is the least desirable option unless specifically addressing stun vulnerabilities.

Act 3 Cruel (Act 6) Reward Choices

The Act 3 Cruel rewards are:

The Venom Draught of the Lost (+10% Chaos Resistance) is typically the superior choice due to the rarity of Chaos Resistance on gear. Only builds utilizing Chaos Inoculation, often paired with Eternal Youth, might prefer the Venom Draught of the Sky (+5 to all Attributes) for its attribute boost.